PCIe NVMe SSD on PCIe slot-Worth it?

I am not familiar with MSI boards, but I did read over the specifications of that motherboard The nvme is in the M2_1 slot? That would be the

You're referring to NVME based M2 SSDs, correct? But yes if the SSD is PCIE spec then of course the speed will be less when used on PCIE

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m2 slot screw Learn to distinguish cards, including slots, keys, sizes, and types Understand slot functionality, and PCIe interfaces, and the platform's